A case of contact dermatitis syndrome caused by Dermabond, followed by contact dermatitis caused by false eyelash glue and Aron Alpha glue: possibility of cross-reactions among cyanoacrylates. Eczema types: Contact dermatitis diagnosis and treatment. Kim, Roderick Y. Disclaimer. for this article. Allergic reactions to 2-octyl cyanoacrylate (Dermabond; Ethicon, Somerville, NJ) are rare in the medical literature; there is only one published report.1 There are, however, scattered anecdotal reports of allergies to Dermabond on the Internet. Laparoscopic and robotic hysterectomy are becoming increasingly popular alternatives to open abdominal procedures. Diffuse Cutaneous Allergic Reaction to Dermabond. Percutan Tech. Gearhart, Peter A. Rash After Surgery: Causes, Diagnosis, Treatment, and When to Worry 2021 Jun 15;34(6):736-738. doi: 10.1080/08998280.2021.1935140. Cleft Palate Craniofac. Dermabond is a liquid topical skin adhesive containing a monomeric 2-octyl cyanoacrylate formulation and the colorant D&C Violet #2 which should slough off with desquamation of the epidermis 7-14 days after application. Three additional trocars were placed in the right lower quadrant, left lower quadrant and at the umbilicus. White, Andrew A. Postoperative results following the resolution of this allergic reaction are shown in Figure 3. H\n@C 3,9Fa} c/vMDZ$qvoxnS1>[yos,:? Continuous variables were analyzed with simple logistic regression, and categorical variables were analyzed using the chi-square test or Fisher exact test, as appropriate. Hysterectomy is the surgical removal of the uterus. 0000047688 00000 n gynaecology, allergic reaction, Dermabond. A healthy 36-year-old white woman with a deflated silicone gelfilled breast implant underwent uneventful removal of her implants, bilateral capsulotomies, replacement of her implants with 325-cc silicone gelfilled implants, and bilateral mastopexies. Arthur W. Perry, MD, Michael Sosin, Severe Allergic Reaction to Dermabond, Aesthetic Surgery Journal, Volume 29, Issue 4, July 2009, Pages 314316, https://doi.org/10.1016/j.asj.2009.02.019. Nine patients had positive patch test results to Dermabond; six had developed secondary generalization.The mean time between Dermabond application and ACD onset was 34 days (range, 27-44) in six patients with ACD after the first use, whereas, in the other three patients, it was 5.6 days (range, 4-8) after the second use. Rabah, Sari Monzer B, Two months after breast augmentation/mastopexy and resolution of her allergic reaction to Dermabond. Clipboard, Search History, and several other advanced features are temporarily unavailable. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. 0000014217 00000 n Background: The clinical characteristics of patients with allergic contact dermatitis (ACD) due to a skin adhesive containing 2-octyl cyanoacrylate, Dermabond, have not yet been elucidated. Dermabond is a skin adhesive used to close wounds, according to FamilyDoctor.org 2. Poore, Samuel O. Farmer, Rebecca L. } Moschos M, Droutsas D, Boussalis P, Tsioulias G (1997) Clinical experience with cyanoacrylate tissue adhesive. J.S.C. Plast. Hamilton, Canada. It can have many causes, from Zika virus to allergies. Twenty of 739 (2.7%) patients using 2-octyl cyanoacrylate and nine of 406 (2.2%) patients using n-butyl cyanoacrylate showed ACD. 2020. Caton AM, Dauphine C (2014) Allergic contact dermatitis after repeated exposure to Dermabond. In vivo study of wound bursting strength and compliance of topical skin adhesives. It. sharing sensitive information, make sure youre on a federal In this retrospective cohort study, we evaluated the incidence and characteristics of contact dermatitis (type IV hypersensitivity reaction) post application of Dermabond (Trade name PRINEO . 0000013256 00000 n Clin. By submitting a comment you agree to abide by our Terms and Community Guidelines. Scientific Reports (Sci Rep) Allergy Clin. She was afebrile and looked well. The dermatologist diagnosed ACD based on history of exposure, morphology (well-demarcated pruritic eczematous eruptions, papules, or vesicles), and regional distribution (localized in the area of skin that was exposed to skin adhesives) (Fig. 0000059825 00000 n Contact Dermatitis from Dermabond : Plastic and Reconstructive - LWW The distinction between infection and contact dermatitis is critical. None of the variables was found to increase the risk of ACD. A randomized trial comparing octylcyanoacrylate tissue adhesive and sutures in the management of lacerations. : A Review of the Literature. 2019. A severe allergic reaction can be seen; erythema and pruritis are both present along the incisions where Dermabond was applied. None of the patients received systemic steroid therapy or wound revision. sustainable solutions for society. An official website of the United States government. Although there are only a few surgical cases reported regarding allergic reaction to topical application of 2-octyl cyanoacrylate, the current literature is rife with allergic reaction to other cyanoacrylate formulations especially when used during previous surgeries as outlined (Table 1) [13,15-24]. The variables used to determine the risk factors of ACD to topical skin adhesives were retrieved from electronic medical records. Dermabond-induced ACD is apparently characterized by a high prevalence of primary sensitization at first exposure to Dermabond, secondary generalization is frequent, and most patients show cross-reactivity to ethyl cyanoacrylate. & Thode, H. C. Jr. A review of the literature on octylcyanoacrylate tissue adhesive. Plastic surgeons now use Dermabond for emergency room laceration repairs3 and for cosmetic surgery.4 Dermabond allows for the rapid closure of wounds while eliminating cross- and point-marks associated with suture closure. 0000098852 00000 n 0000060590 00000 n Work as a cosmetician with regular exposure to cyanoacrylate-based eyelash extension glue has also been linked to occupational asthma and allergic rhinitis [27]. As no definite factors related to the development of allergic contact dermatitis to topical skin adhesives are known, the variables that have been suspected to correlate with type IV hypersensitivity were included in the investigation, along with patient characteristics20,21,22. Severe dermatitis from Dermabond (R) surgical glue Krishnan, R., MacNeil, S. D. & Malvankar-Mehta, M. S. Comparing sutures versus staples for skin closure after orthopaedic surgery: systematic review and meta-analysis. Background: Treatment is simple and most cases will resolve within a few weeks. In conclusion, ACD, while uncommon, occurs in 23% of patients who used 2-octyl cyanoacrylate or n-butyl cyanoacrylate topical skin adhesives. Surg. Nine patients had positive patch test results to Dermabond; six had developed secondary generalization.The mean time between Dermabond application and ACD onset was 34 days (range, 27-44) in six patients with ACD after the first use, whereas, in the other three patients, it was 5.6 days (range, 4-8) after the second use. Interestingly, Nakagawa et al.25 reported a 7.0% incidence of ACD in 100 patients who underwent breast reconstruction surgery. The authors declare no competing interests. 69, 763781 (2012). Care must be taken to treat the symptoms of the allergic reaction while maintaining the integrity of the surgical incisions. (2015). Topical skin adhesives were applied according to the instruction manual of each product. El-Dars LD, Chaudhury W, Hughes TM, Stone NM (2010) Allergic contact dermatitis to Dermabond after orthopaedic joint replacement. Fibrin glue versus N-butyl-2-cyanoacrylate in corneal perforations. This report describes a rare case of a diffuse cutaneous allergic reaction to Dermabond following its use to close a surgical incision, its prompt identification, and treatment after presentation to an emergency department. Fam. to worldwide, enabling them to utilize available resources effectively. Ricci JA, Parekh NN, Desai NS. The authors describe the first case series of ACD to Dermabond Prineo where patch testing confirmed the diagnosis in all patients. Orthopedics. Providing cutting-edge scholarly communications Bethesda, MD 20894, Web Policies Skin inflammation and pruritus abated completely within 2 days. Skin patch testing performed three years after initial presentation was positive for ethyl cyanoacrylate. 0000068746 00000 n and PubMedGoogle Scholar. HysterSisters.com is a patient support website and does not intend to take the place of the relationship between patient and personal physician. For wound dehiscence, adhesive tape was applied to the margins of the wound. We deduced that this is due to its lower popularity than 2-octyl cyanoacrylate as a topical skin adhesive. The number is still staggering even though some estimate that the number of hysterectomies has been steadily declining over the last decade from a peak of 681,234 performed in 2002 to 433,621 cases reported in 2010. Of the three excluded patients, one had scabies and two had dyshidrotic eczema. : study design, and data analysis. Its medical use quickly spread and interestingly, the first reported use of a cyanoacrylate tissue adhesive on the human eye occurred in 1968 [11]. 156, 577578 (2021). First, patch tests were not conducted on all suspected patients to diagnose ACD, so the accuracy of the diagnosis could be doubted. the suspicion of an allergic reaction to Dermabond and recommended application of a thin topical layer of hydrocortisone 1% to affected areas 2-4 times per day. A rash can be an early symptom of a life threatening allergic reaction called anaphylaxis. Elzomor, Amir Contraindications to Dermabond use include cyanoacrylate or formaldehyde allergy. community, Department of Obstetrics, Gynaecology and Reproductive Science Icahn School of Medicine at Mount Sinai New York, New York, USA, Chairman, Department of Obstetrics and Gynaecology Western Connecticut Health Network, Danbury, CT, USA. In addition, since the agent used for postoperative wound dressing was the same as that used for preoperative skin preparation, the area of the rash or erythema would have been more extensive than that of the topical skin adhesive if the patient was allergic to the dressing agent. Skin inflammation and pruritus abated completely within two days. The site is secure. Slider with three articles shown per slide. Y.H.P. 8 Days Post Hysterectomy Allergic Reaction to Dermabond - Help. Dermatitis. 0000007745 00000 n However, in this study, the use of topical skin adhesive did not differ by sex, and the incidence of ACD was also not affected by sex. The use of 2-octyl cyanoacrylate (Dermabond; Ethicon, Somerville, NJ) for wound closure is increasingly popular. Dumville JC, Coulthard P, Worthington HV, et al. Commentary on: Does Implant Surface Texture Affect the Risk of Capsular Contracture in Subglandular Breast Augmentation and Breast Augmentation-Mastopexy? scholarly communications through the effective use of editorial and The clinical characteristics of patients with allergic contact dermatitis (ACD) due to a skin adhesive containing 2-octyl cyanoacrylate, Dermabond, have not yet been elucidated. 0000061721 00000 n Article May 2014 Amy Caton Christine E Dauphine View Severe dermatitis from Dermabond (R) surgical glue Article Oct. Ardis AE (1949) US patent nos. and This site needs JavaScript to work properly. Reconstr. After approval from the local ethics committee (Korea University Guro Hospital Institutional Review Board, No. Durando, D. et al. Post-surgical contact dermatitis is a localized rash that is almost always a reaction to something that came into contact with your skin. The .gov means its official. Ther. We report a case of a fulminant allergic reaction to Dermabond following a mastopexy. Dr. Perry was previously a paid consultant to Ethicon, a Division of Johnson & Johnson and the makers of Dermabond. The .gov means its official. Accessibility Jurado-Palomo J, Caballero T, Fernndez-Nieto M, Quirce S (2009) Occupational asthma caused by artificial cyanoacrylate fingernails. Your doctor should be notified of any symptoms of infection, so treatment can begin immediately. Render date: 2023-05-01T15:29:35.649Z government site. A prospective, randomized controlled trial comparing n-butyl cyanoacrylate tissue adhesive (LiquiBand) with sutures for skin closure after laparoscopic general surgical procedures.
Cerakote Gun Finish Simulator, Glock Ejector Rubbing On Slide, Landscape Prints Framed, Shirley Booth Net Worth At Her Death, Articles D